畜牧兽医学报2018，Vol.49Issue(1)：1-9,9.DOI:10.11843/j.issn.0366-6964.2018.01.001
中国猪繁殖与呼吸综合征病毒流行历史及现状
The Prevalent History and Current Status of Porcine Reproductive and Respiratory Syndrome in China
摘要
Abstract
Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically important diseases in the world.It has been more than twenty years since the first report in China.The objective of this paper is to analyse the prevalent history and current status through a perspective of epidemiology,aiding to the prevention of PRRS virus (PRRSV).Both genotype 1 and genotype 2 PRRSV are prevalent in China.For genotype 2,majority of epidemic strains in the fields were clustered into four lineages (lineage 8,lineage 5,lineage 3 and lineage 1),among which lineage 8 (highly pathogenic PRRSV-like) and lineage 1 (NADC30-1ike) are dominant viruses.The genome homology between BJ-4 and VR2332 is 99.6％,which suggested that BJ-4 was probably imported from North America region.For genotype 1,all the isolated strains in China belong to subtype 1 and were detected in more than 9 provinces/regions.The Chinese isolated strains have highly conserved amino acid mutation sites on the GP5 and N protein compared with Lelystad virus.关键词
猪繁殖与呼吸综合征病毒/分子流行病学/基因Ⅰ型/基因Ⅱ型/蓝耳病Key words
porcine reproductive and respiratory syndrome virus/molecular epidemiology/genotype 1/genotype 2/PRRS分类
农业科技引用本文复制引用
郭振华,陈鑫鑫,李睿,乔松林,郭军庆,张改平..中国猪繁殖与呼吸综合征病毒流行历史及现状[J].畜牧兽医学报,2018,49(1):1-9,9.基金项目
国家重点研发计划(2016YFD0500709) （2016YFD0500709）
国家生猪产业技术体系专项基金项目(CARS-35) （CARS-35）
