首页|期刊导航|药物分析学报(英文)|A liquid chromatography with tandem mass spectrometry method for quantitating total and unbound ceritinib in patient plasma and brain tumor
药物分析学报(英文)2018,Vol.8Issue(1):20-26,7.
A liquid chromatography with tandem mass spectrometry method for quantitating total and unbound ceritinib in patient plasma and brain tumor
A liquid chromatography with tandem mass spectrometry method for quantitating total and unbound ceritinib in patient plasma and brain tumor
摘要
关键词
Ceritinib/Reversed-phase liquid chromatography with tandem mass spectrometry(LC–MS/MS)/Fraction unbound in plasma/Fraction unbound in brain tissue/Brain tumor penetration/Unbound brain-to-plasma partition coefficientKey words
Ceritinib/Reversed-phase liquid chromatography with tandem mass spectrometry(LC–MS/MS)/Fraction unbound in plasma/Fraction unbound in brain tissue/Brain tumor penetration/Unbound brain-to-plasma partition coefficient引用本文复制引用
Xun Bao,Jianmei Wu,Nader Sanai,Jing Li..A liquid chromatography with tandem mass spectrometry method for quantitating total and unbound ceritinib in patient plasma and brain tumor[J].药物分析学报(英文),2018,8(1):20-26,7.基金项目
This study was supported by the United States Public Health Service Cancer Center Support Grant P30 CA022453. We thank Novartis for providing the study drug and isotope-labeled internal standard and providing financial support for the clinical study. We particularly thank the patients enrolled in the study. ()