中国动脉硬化杂志2018，Vol.26Issue(2)：171-175,5.
血管内膜中膜自动跟踪技术评价颈动脉孤立性斑块生物力学特性
Biomechanical characteristics of carotid isolated plaques using intima-media thickness automatic tracking technique
摘要
Abstract
Aim To assess the biomechanical characteristics of carotid isolated plaques using intima-media thickness (IMT) automatic tracking technique.Methods The study included 30 patients who had isolated plaques in carotid artery.IMT strain rate (SR),IMT time strain rate (TR) and AIIc％ were measured by IMT automatic tracking technique along with acoustic densitometry (AD) to assess the variation of the IMT and acoustic density in the upstream,fibrous cap top and downstream regions of the plaque and ipsilateral normal carotid.All plaques were divided into three groups according to IMT:small group (1.2 mm＜IMT＜l.5 mm),moderate group (1.5 mm＜IMT＜2.5 mm) and large group (IMT＞2.5 mm).The differences of SR,TR and AIIc％ were identified among three groups.Results SR and TR were significantly reduced in plaques group compared with controls.Compared with cap top area(CTA),the SR of up-stream area (UA) were significantly increased.However,the SR,TR of downstream area (DA) were significantly lower than CTA and UA.Compared with control,the SR,TR were significantly reduced in CTA and DA.AIIc％ in UA and CTA were significantly lower than DA.AIIc％ in all three regions were significantly higher than that in control group.The SR,TR for the 3 plaque regions were negatively correlated with AIIc％ (r=-0.63,r=-0.58,P＜0.05).The SR,TR among three groups showed no statistical significance.Conclusion IMT automatic tracking along with AD could be applied to identify the anisotropic biomechanical features in carotid isolated plaques,which may be a new noninvasive way to early assess the biomechanical properties of carotid plaque.关键词
血管内膜中膜自动跟踪技术/颈动脉孤立性斑块/力学特性/声学密度定量技术Key words
Intima-media thickness automatic tracking technique/Carotid isolated plaques/Biomechanical characteristics/Acoustic densitometry分类
医药卫生引用本文复制引用
李妙,张平洋,马小五,董静,吴文芳,丁钱山..血管内膜中膜自动跟踪技术评价颈动脉孤立性斑块生物力学特性[J].中国动脉硬化杂志,2018,26(2):171-175,5.基金项目
南京市2015年度科技发展计划(医疗卫生与国际合作)项目(201503022) （医疗卫生与国际合作）
