中国动脉硬化杂志2018，Vol.26Issue(2)：207-212,6.
β3肾上腺素受体与心血管疾病相关性的研究进展
Research progress of the relationship between β3-adrenoceptor and cardiovascular diseases
摘要
Abstract
Cardiovascular diseases,such as myocardial infarction,chronic heart failure,are the main causes of human death.It is clear that lipid metabolic dysfunction,diabetes and so on are important risk factors for the occurrence and development of cardiovascular diseases.Changes in myocardial structure,Ca2+ signaling,cellular metabolism,oxidative stress,activation of renin-angiotensin system and mitochondrial dysfunction are associated with the development of cardiovascular diseases.Since β3-adrenoceptor (β3-AR) has been cloned in 1989,the researchers have found that β3-AR is associated with cardiovascular diseases.β3-AR stimulation can regulate lipid metabolism,improve cardiac function and remodeling,therefore,perhaps prevent and treat cardiovascular diseases.关键词
β3肾上腺素受体/心血管疾病/动脉粥样硬化Key words
β3-adrenoceptor/Cardiovascular diseases/Atherosclerosis分类
医药卫生引用本文复制引用
张梓桑,张薪茹,李光宇,张劲松,杜荣增..β3肾上腺素受体与心血管疾病相关性的研究进展[J].中国动脉硬化杂志,2018,26(2):207-212,6.基金项目
镇江市社会发展基金项目(SH2015036) （SH2015036）
