中国感染控制杂志2018，Vol.17Issue(1)：6-9,4.DOI:10.3969/j.issn.1671-9638.2018.01.002
某院2016年ICU与普通病房铜绿假单胞菌耐药性对比分析
Comparison of antimicrobial resistance of Pseudomonas aeruginosa from intensive care units and general wards in a hospital in 2016
摘要
Abstract
Objective To investigate the distribution and antimicrobial resistance of Pseudomonas aeruginosa (P.aeruginosa) from intensive care units(ICUs) and general wards of a hospital,and provide scientific basis for rational use of antimicrobial agents in clinic.Methods Identification and antimicrobial susceptibility testing of clinically isolated bacteria in this hospital in 2016 were performed by VITEK 2 Compact automatic microbial analysis system,difference in antimicrobial resistance of P.aeruginosa between ICUs and general wards was compared.Results The tested specimens were mainly sputum in both ICUs and general wards,accounting for 78.7％ and 66.5％ respectively.There was no significant difference in the isolation rate of P.aeruginosa between ICUs and general wards (11.7％ vs 11.0％,P＞0.05).P.aeruginosa isolated from ICUs had the highest resistance rate to aztreonam (73.8％),resistance rates to piperacillin/tazobactam,cefoperazone/sulbactam,ceftazidime,imipenem,and meropenem were all up to more than 50％;P.aeruginosa detected in general wards had the highest resistance rate to aztreonam(59.6 ％),followed by piperacillin/tazobactam and imipenem,accounting for 48.0 ％ and 44.3 ％ respectively;resistance rates of P.aeruginosa isolated from ICUs to 12 kinds of antimicrobial agents were all higher thanthose of general wards(P＜0.05).Conclusion Resistance rate of P.aeruginosa from ICUs is higher than that in general wards,which should be paid attention,antimicrobial agents should be selected for clinical treatment of infection according to the results of antimicrobial susceptibility testing result.关键词
ICU/普通病房/感染/铜绿假单胞菌/抗药性,微生物/耐药性Key words
intensive care unit/general ward/infection/Pseudomonas aeruginosa/drug resistance/microbial分类
医药卫生引用本文复制引用
税剑,邹明祥,李军,王海晨,黄紫嫣,胡咏梅,刘文恩..某院2016年ICU与普通病房铜绿假单胞菌耐药性对比分析[J].中国感染控制杂志,2018,17(1):6-9,4.基金项目
湖南省自然科学基金(14JJ7003) （14JJ7003）
湖南省发改委(湘发改高技[2012]1493号 （）
湘发改投资[2014]658号) （）
