中国感染控制杂志2018，Vol.17Issue(1)：31-35,5.DOI:10.3969/j.issn.1671-9638.2018.01.007
2016年武汉地区住院儿童人博卡病毒感染的临床特征及流行病学
Clinical and epidemiological features of human Bocavirus infection in hospitalized children in Wuhan area
摘要
Abstract
Objective To understand infection status,clinical and epidemiological features of respiratory tract infection(RTI) with human Bocavirus(HBoV) in children in Wuhan area.Methods A total of 968 hospitalized children with acute RTI between January and December 2016 were recruited in the study.Sputum specimens were collected by sterile negative pressure suction method.HBoV,respiratory syncytial virus,adenovirus,A/B-type influenza virus,and parainfluenza virus Ⅰ/Ⅱ/Ⅲ were detected,the prevalence and clinical features of HBoV infection were analyzed.Results Among 968 cases,75(7.75％) were positive for HBoV.The detection rates of HBoV in boys and girls were 5.68％ and 2.07％ respectively,there was no significant difference in the detection rate of HBoV between different genders(x2 =2.083,P =0.140);53 (70.67 ％) HBoV-positive children were＜ 1 year old,63(84.00％) were＜3 years old,there was significant difference in the detection rate among all age groups(x2 =4.60,P =0.043).The detection rates in spring,summer,autumn,and winter were 9.78％,5.29％,2.86％,and 5.20％ respectively;except September and October,HBoV was found positive in the other months,detection rate was highest in March (33.33％).17 cases were simple HBoV infection and 58 were mixed infection,the main clini cal diagnosis of HBoV was bronchopneumonia(n =26,34.67％).The main clinical features of HBoV cases were fever(81.33 ％),cough(77.33 ％),and wheezing (77.33 ％).Conclusion HBoV is one of the important pathogens causing RTI in hospitalized children in Wuhan area,HBoV infection can occur throughout the year,the peak season are spring and summer,there is no difference between different genders.The most common clinical diagnosis of HBoV in hospitalized children is bronchopneumonia,the main manifestations are fever,coughing,and wheezing.关键词
儿童/呼吸道感染/人博卡病毒/临床特征Key words
child/respiratory tract infection/human Bocavirus/clinical feature分类
医药卫生引用本文复制引用
王瑢,丁淑贤,王娟丽,鲍星星,边俊梅..2016年武汉地区住院儿童人博卡病毒感染的临床特征及流行病学[J].中国感染控制杂志,2018,17(1):31-35,5.基金项目
武汉市卫生计生委医疗卫生科研项目(WG15D04) （WG15D04）
湖北省卫生和计划生育委员会科研项目(WJ2017M186) （WJ2017M186）
