中国康复理论与实践2018，Vol.24Issue(2)：160-164,5.DOI:10.3969/j.issn.1006-9771.2018.02.008
脊髓损伤后脑源性神经营养因子神经生物学效应的研究进展
Neurobiological Effect of Brain-derived Neurotrophic Factor after Spinal Cord Injury(review)
摘要
Abstract
Spinal cord injury(SCI)can lead to varying degrees of somatic and autonomic dysfunction and seriously affect the quali-ty of life of patients.The neurobiology and function promotion effects of brain-derived neurotrophic factor(BDNF)after SCI have been extensively studied,including neuroprotection,neuroplasticity and process regulation of neuroinflamma-tion,etc.,as well as functional recovery.However,the adverse effects of BDNF after SCI,such as neuropathic pain and spasticity,were also studied.关键词
脊髓损伤/脑源性神经营养因子/神经修复/痉挛/神经病理性疼痛/综述Key words
spinal cord injury/brain-derived neurotrophic factor/neural repair/spasticity/neuropathic pain/review分类
医药卫生引用本文复制引用
李向哲,王灿,吴勤峰,王彤..脊髓损伤后脑源性神经营养因子神经生物学效应的研究进展[J].中国康复理论与实践,2018,24(2):160-164,5.基金项目
1.国家自然科学基金面上项目(No.81672258) （No.81672258）
2.苏州科学技术局民生科技项目(No.SYS201785)Supported by National Natural Science Foundation of China(General)(No.81672258)and Livelihood Science and Technology Program of Suzhou Science and Technology Bureau(No.SYS201785) （No.SYS201785）
