中国临床医学2017，Vol.24Issue(6)：868-872,5.DOI:10.12025/j.issn.1008-6358.2017.20170502
丘脑底核磁共振成像技术研究进展
Recent progresses of magnetic resonance imaging of subthalamic nucleus
摘要
Abstract
Subthalamic nucleus (STN) is the main target nucleus for deep brain stimulation (DBS) treatment in patients with Parkinson disease.To implant the electrode on the sensorimotor part of STN individually and accurately,the boundary of STN is required to be clarified clearly on the magnetic resonance imaging (MRI) without geometric distortion.At present,there are three categories of MRI sequences:spin echo sequence including T2-weighted imaging (T2WI),inversion recovery (IR),diffusion tensor imaging (DTI),and fractional anisotropy (FA);magnetization transfer technique including magnetic susceptibility weighted imaging (SWI) and T2-weighted magnitude imaging (T2 * WI);image reconstruction technique such as quantitative susceptibility mapping (QSM).It is found that QSM can provide optimal signal-noise ratio to identify the boundary of STN,T2 * technique comes second.T2WI has high geometric accuracy when the patients wear frame,which is appropriate for direct DBS implantation on STN with frame.关键词
丘脑底核/磁共振成像/脑深部电刺激/帕金森病Key words
subthalamic nucleus/magnetic resonance imaging/deep brain stimulation/Parkinson disease分类
医药卫生引用本文复制引用
孔维诗,路明宽,阳青松,陈智昌,仇一青,吴曦..丘脑底核磁共振成像技术研究进展[J].中国临床医学,2017,24(6):868-872,5.基金项目
国家重点研发计划“数字诊疗装备研发”试点专项课题(2016YFC0105900).Supported by "Digital Equipment of Diagnosis and Treatment" Special Program of National Key Research and Development Plan (2016YFC0105900). （2016YFC0105900）
