中国药业2018,Vol.27Issue(3):1-6,6.DOI:10.3969/j.issn.1006-4931.2018.03.001
血管平滑肌细胞毒物毒理及机制研究进展
Research Progress of Toxicology and Mechanism of Vascular Smooth Muscle Cells
杨莉 1李涛 1张弘1
作者信息
- 1. 湖北省荆州市第一人民医院药学部,湖北荆州 434000
- 折叠
摘要
Abstract
Cardiovascular disease is seriously endangering the health of human beings. Some substances play important roles in the proliferation, migration, apoptosis and autophagy of vascular smooth muscle cells, which are closely associated with atherosclerosis and directly related to the occurrence and development of cardiovascular diseases. In order to understand the effect and mechanism of substance on vascular smooth muscle cells, the prevention and treatment of cardiovascular disease is further studied. From the perspective of toxicology, this article reviews the toxicology effect and mechanisms on the vascular smooth muscle cells by metal, nonmetal, environmental chemical substances, cardiovascular active substances and so on.关键词
血管平滑肌细胞/汞/铅/砷/环境化学物质/心血管活性物质/毒理/机制/进展Key words
vascular smooth muscle cells/Hg/Pb/As/environmental chemical substances/cardiovascular active substances/toxicology/mechanism/progress分类
医药卫生引用本文复制引用
杨莉,李涛,张弘..血管平滑肌细胞毒物毒理及机制研究进展[J].中国药业,2018,27(3):1-6,6.