中国药业2018，Vol.27Issue(3)：7-11,5.DOI:10.3969/j.issn.1006-4931.2018.03.002
柔肝宝颗粒质量标准研究
Study on Quality Standard of Rouganbao Granules
摘要
Abstract
Objective To establish the quality standard of Rouganbao Granules. Methods The contents of Panax quinquefolium, Scutel-laria baicalensis, Tribulus terrestris, Citrus medica, Angelica sinensis, Bupleurum chinense and Paeona lactiflora in Rouganbao Granules were identified by TLC method. The contents of baicalin, ginsenoside Rg1 and ginsenoside Re in Rouganbao Granules were determined by HPLC method. Results The TLC method was effective, specific and had high separation degree without interference by negative con-trol. The contents of baicalin, ginsenoside Rg1 and ginsenoside Re had good linearity within the ranges of 0. 1236-0. 8652 μg ( r=0. 9998 ) , 2. 572-15. 532 μg ( r=0. 9997 ) , 3. 756-22. 536 μg ( r=0. 9996 ) , respectively. The average recoveries were 99. 75％ , 100. 06％, 99. 93％, the RSDs were 2. 03％, 0. 75％, 1. 93％(n=9). Conclusion The methods were simple, accurate and reproducible, which can be used for the quality control of Rouganbao Granules.关键词
柔肝宝颗粒/质量标准/西洋参/人参皂苷/黄芩Key words
Rouganbao Granules/quality standard/Panax quinquefolium/ginsenoside/Scutellaria baicalensis分类
医药卫生引用本文复制引用
郭小红,冷静,徐冲,刘霞,孙全,冉强,黄祎..柔肝宝颗粒质量标准研究[J].中国药业,2018,27(3):7-11,5.基金项目
重庆市基本科研业务费计划项目(cstc 2015 jbky 330025006 ) （cstc 2015 jbky 330025006 ）
重庆市社会事业与民生保障科技创新专项重点项目(cstc 2016 shms - zd 10001 ). （cstc 2016 shms - zd 10001 ）
