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灵芝浓缩丸制备工艺研究

叶辉岩 马进原 毛景华 出玮婧 朱铉

中国药业2018,Vol.27Issue(3):12-14,3.
中国药业2018,Vol.27Issue(3):12-14,3.DOI:10.3969/j.issn.1006-4931.2018.03.003

灵芝浓缩丸制备工艺研究

Study on Preparation Process of Linzhinongsuo Pills

叶辉岩 1马进原 2毛景华 3出玮婧 2朱铉2

作者信息

  • 1. 厦门大学附属第一医院,福建厦门 361003
  • 2. 厦门大学药学院,福建厦门 361005
  • 3. 武夷山元生泰生物科技有限公司,福建武夷山 354300
  • 折叠

摘要

Abstract

Objective To establish the prescription and preparation method of Linzhinongsuo Pills. Methods The Linzhinongsuo Pills were prepared by plastic molded method. The preparation process of the pills was determined by the indexes such as the ease of making pills, properties of pills, drying time, quality of pills, disintegration time limited and moisture content, and the pills were tested according to the requirements of Chinese Pharmacopoeia. Results The ratio of germination-activating sporoderm-broken ganoderma spores ( GSGS ) and flow extract of Ganoderma lucidum ( or Ganodelma sinense ) was 1:2, and the pills were polished after drying 5 h at 60 ℃ in drying oven, and then the pills were dried for 1 h at 60 ℃. The prepared Linzhinongsuo Pills had good pellets and smooth surface, the water content and disintegration time limited were in accordance with the requirements of Chinese Pharmacopoeia. Conclusion The preparation process of Linzhinongsuo Pills by plastic molded method was simple , which is suitable for industri al production.

关键词

灵芝/三萜/多糖/浓缩丸/塑制法

Key words

Ganoderma lucidum ( or Ganodelma sinense )/triterpenoid/polysaccharide/condensed pill/plastic molded method

分类

医药卫生

引用本文复制引用

叶辉岩,马进原,毛景华,出玮婧,朱铉..灵芝浓缩丸制备工艺研究[J].中国药业,2018,27(3):12-14,3.

基金项目

福建省科技计划社会发展引导性(重点)项目[ 2014Y0074 ]. (重点)

中国药业

OACSTPCD

1006-4931

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