中国药业2018，Vol.27Issue(3)：15-18,4.DOI:10.3969/j.issn.1006-4931.2018.03.004
龙匙片活血化瘀作用研究
Research on Activating Blood Circulation to Dissipate Blood Stasis Effect of Longchi Tablets
孙会静 1李丽2
作者信息
- 1. 广西壮族自治区人民医院,广西南宁 530021
- 2. 广西中医药大学,广西南宁 530222
- 折叠
摘要
Abstract
Objective To verify the effect of Longchi Tablets on activating blood circulation to dissipate blood stasis by several methods and animal models, and provide the evidences for its clinical use. Methods The acute blood-stasis rats models were established by hypo-dermic injection of adrenergic(AD) after swimming in ice water, the effect of Longchi Tablets on hemorheology was observed. The mesenteric microcirculatory disturbance rats models were established by injected with adrenergic, the effect of Longchi Tablets on microcirculatory disturbance was observed. The effect of Longchi Tablets on PT and APTT was observed by in vitro method. Results Longchi Tablets could significantly reduce the plasma viscosity, whole blood viscosity, blood fibrinogen concentration, erythrocyte sedimentation and platelet adhesion rate of the rats, it could inhibit the narrowing of the arteriole diameter of the mesenteric microcirculation, slow blood flowing rate, reduction of open capillary and the change of the blood flow pattern in rats, and could prolong the PT and APTT. Conclusion Longchi Tablets can improve the hemorheology and microcirculatory disturbance, and have the ability of activating blood circulation to dissipate blood stasis.关键词
龙匙片/活血化瘀/微循环障碍/SD大鼠Key words
Longchi Tablets/activating blood circulation to dissipate blood stasis/microcirculatory disturbance/SD rats分类
医药卫生引用本文复制引用
孙会静,李丽..龙匙片活血化瘀作用研究[J].中国药业,2018,27(3):15-18,4.
