中国药业2018，Vol.27Issue(4)：10-12,3.DOI:10.3969/j.issn.1006-4931.2018.04.004
清补通络浓缩丸提取工艺优化研究
Study on Extraction Process of Qingbutongluo Concentrated Pills
摘要
Abstract
Objective To optimize the extraction process of Qingbutongluo Concentrated Pills. Methods The content of baicalin was determined by HPLC,and the optimum extraction process was optimized by orthogonal test with the content of baicalin and the yield of extraction as the indexes. Results The optimum extraction process was as follows:the ratio of material to liquid was 1 :10 with 2 times of extraction,1 h each time. Under this condition,the content of baicalin was 4. 49 mg/g,and the yield of extraction was 4. 84％. Conclusion The optimized extraction process is reasonable,stable and effective,which can provide the experimental basis for the pro-duction of Qingbutongluo Concentrated Pills and other new medicines of traditional Chinese medicine.关键词
清补通络浓缩丸/黄芩苷/高效液相色谱法/提取工艺/优化Key words
Qingbutongluo Concentrated Pills/baicalin/HPLC/extraction process/optimization分类
化学化工引用本文复制引用
王林,王婷媛,邱远金,林芳花,周卫刚,刘纪杉,李江涛,朱国强,高辉..清补通络浓缩丸提取工艺优化研究[J].中国药业,2018,27(4):10-12,3.基金项目
新疆维吾尔自治区中医民族医药管理局新疆地产中药民族药新药研发培育项目[ 2016-02-07 ]. （）
