中国药业2018，Vol.27Issue(4)：32-34,3.DOI:10.3969/j.issn.1006-4931.2018.04.011
生长抑素用于老年术后早期炎性肠梗阻的临床研究
Clinical Study on Somatostatin for Treating Elderly Patients with Early Postoperative Inflammatory Small Bowel Obstruction
摘要
Abstract
Objective To investigate the clinical effect of somatostatin in treating elderly patients with early postoperative inflammatory small bowel obstruction(EPISBO). Methods Totally 119 elderly patients with EPISBO were randomly divided into the control group(59 cases) and the treatment group(60 cases). The control group was treated with conventional treatment,while the treatment group were treated with conventional treatment combined with somatostatin. The two groups were treated for 7 d. Results The total effective rate of the treatment group was 93. 33％,which was significantly higher than 72. 88％ of the control group(χ2=8. 899,P=0. 003). The abdominal symptoms relief time,bowel sounds recovery time,anus exhaust recovery time,nausea disappear time,gastrointestinal decom-pression drainage volume and cure time of the treatment group were significantly shorter than those of the control group(P < 0. 05). After treatment,the serum levels of CRP,IL-6 and TNF-α in the two groups were significantly lower than those before treatment,and those in the treatment group were significantly lower than those in the control group(P < 0. 05). Conclusion Somatostatin in the treat-ment of elderly patients with EPISBO has good effect and safety,it can quickly improve the clinical symptoms,shorten the course of the disease and reduce the intestinal inflammation reaction,which is worthy of clinical promotion.关键词
生长抑素/早期炎性肠梗阻/老年/疗效Key words
somatostatin/early postoperative inflammatory small bowel obstruction/elderly/curative effect分类
医药卫生引用本文复制引用
封士冬,廖芝伟,吴钢,周远航..生长抑素用于老年术后早期炎性肠梗阻的临床研究[J].中国药业,2018,27(4):32-34,3.基金项目
上海市宝山区医学特色专科资助项目[ BSIK-2014-B01(02)]. （02）
