中国肿瘤生物治疗杂志2018，Vol.25Issue(1)：17-22,6.DOI:10.3872/j.issn.1007-385x.2018.01.003
精准医学与膀胱癌的个体化诊疗
Precise medicine and individualized diagnosis and treatment of bladder cancer
毛凯晟 1阎海2
作者信息
- 1. 北京泛生子基因科技有限公司,北京102206
- 2. 美国杜克大学医学中心病理系Preston Robert Tisch脑肿瘤中心,美国北卡罗来纳州达勒姆
- 折叠
摘要
Abstract
Bladder cancer is one of the most common malignant tumors of urinary system.It has been more and more difficult to diagnose and treat bladder cancer with old clinical models.Neo-biomarkers and actionable targets emerge with the incoming big data such as TCGA (the cancer genome atlas),MSK-IMPACT (Memorial Sloan-Kettering-integrated mutation profiling of actionable cancer targets),and HPA (human protein atlas) etc,providing more sufficient and reliable basis for the precise diagnosis,treatment and prognosis of bladder cancer.Precision medicine systems based on clinical data and omics information will be applied to the clinic more widely.More investment from government,lower cost and the constant development in new techniques represented with NGS (next generation sequencing) and liquid biopsy all make the precision medicine available from bench to bed,which will provide patients with more accurate and effective diagnosis and treatment.Here,we mainly summarize the development of precision medicine and its study and clinical application in bladder cancer.关键词
膀胱癌/精准医学/基因组学/液体活检/大数据Key words
bladder cancer/precision medicine/genomics/liquid biopsy/big data分类
医药卫生引用本文复制引用
毛凯晟,阎海..精准医学与膀胱癌的个体化诊疗[J].中国肿瘤生物治疗杂志,2018,25(1):17-22,6.
