安徽农业科学2018，Vol.46Issue(4)：73-76,4.
2株海洋红酵母突变菌株对小鼠的毒性试验
Toxicity Test of Two Mutation Strains of Marine Rhodotorula on Mice
摘要
Abstract
[Objective] To study the acute toxicity of two mutation strains of marine Rhodotorula on mice.[Method] 42 mice were randomly divided into 7 groups.Mice in test group ①,②,③ were fed with Rhodotoruda mucilaginosa J6-82 bacteria suspension with the bacteria number of 1 × 107,1 × 109 and 1 × 1011 ind./mL respectively.Mice in testl group ④,⑤,⑥ were fed with Rhodotorula glutinis J2-75 with bacteria number of 1 × 107,1 × 109,1 × 1011 ind./mL respectively.The mice in control group were fed with sterilized red yeast culture medium.The acute toxicity of R.mucilaginosa J6-82 and R.glutinis J2-75 on mice were studied.[Result] 42 mice were clinical healthy,there was no incidence of death or pathological changes.There was no significant difference between the control group and test groups in average body mass,drinking water amount,organ index of mice,but total lymphocyte count and lymphocyte ratio had significant differences between test groups and control group.There was no histopathological change in liver tissue of mice in test groups.[Conclusion] Rhodotonla mucilaginosa J6-82 and Rhodotorula glutinis J2-75 had no acute toxicity on mice.关键词
胶红酵母J6-82/粘红酵母J2-75/毒性试验/小鼠Key words
Rhodotorula mucilaginosa J6-82/Rhodotorula glutinis J2-75/Toxicity test/Mice分类
农业科技引用本文复制引用
刘影,谢为天,吴娟,徐春厚..2株海洋红酵母突变菌株对小鼠的毒性试验[J].安徽农业科学,2018,46(4):73-76,4.基金项目
广东省科技计划项目(2013B020307013) （2013B020307013）
广东省科技计划项目(2017A02021) （2017A02021）
湛江市科技计划项目(2015B01013). （2015B01013）
