分析测试学报2017，Vol.36Issue(11)：1380-1386,7.DOI:10.3969/j.issn.1004-4957.2017.11.015
7种生物碱在不同粒径卷烟主流烟气气溶胶中的分布研究
Distribution of 7 Alkaloids in Aerosol of Various Particle Sizes from Mainstream Cigarette Smoke
摘要
Abstract
A method was developed for the analysis of 7 alkaloids in mainstream cigarette smoke aerosol by gas chromatography-mass spectrometry.By using electrical low-pressure impactor (ELPI),particles of cigarette smoke aerosol were divided into 12 stages and collected.The content and concentration distributions of 7 alkaloids with respect to smoke aerosol particle size were investigated.The collected aerosol particles were treated by alkali extraction method with sodium hydroxide solution and dichloromethane.The extract was separated with a DB-5 MS capillary column under selected ion monitoring(SIM) mode.The targets were quantitatively analyzed using internal standard method.The results showed that,the relative standard deviations (RSDs) for the established method ranged from 2.1％ to 6.4％,with limits of detection(LODs) of 0.39-14.84 ng/cig,and the recoveries at three spiked levels ranged from 85.5％ to 124.8％.All of 7 alkaloids mainly distributed in aerosol of medium size particles(0.144-0.722 μm) with a peak content at particle size of 0.431 tμm,which was similar to the distribution pattern of collected particle mass.The concentrations of 7 alkaloids were uniform throughout the particles of various sizes,indicating a non-specificity distribution.关键词
主流烟气/气溶胶/生物碱/粒径分布/气相色谱-质谱法Key words
mainstream smoke/aerosol/alkaloids/size distribution/gas chromatography-mass spectrometry分类
化学化工引用本文复制引用
朱琴,刘志华,朱瑞芝,杨国荣,张凤梅,张建荣,王亚明,司晓喜..7种生物碱在不同粒径卷烟主流烟气气溶胶中的分布研究[J].分析测试学报,2017,36(11):1380-1386,7.基金项目
云南中烟工业有限责任公司科技开发项目资助(2016JC04) （2016JC04）
