海南医学院学报2018，Vol.24Issue(4)：527-529,533,4.DOI:10.13210/j.cnki.jhmu.20180205.002
重症急性胰腺炎血清降钙素原含量对感染程度、肠黏膜屏障功能的评估价值
The value of serum procalcitonin content in severe acute pancreatitis for evaluating the in-fection degree and intestinal mucosal barrier function
摘要
Abstract
Objective:To explore the value of serum procalcitonin content in severe acute pancreatitis for evaluating the infection degree and intestinal mucosal barrier function.Methods:68 patients with severe acute pancreatitis who were treated in our hospital between January 2015 and September 2017 were selected as pancreatitis group,and 50 healthy volunteers who un-derwent physical examination in this hospital during the same period were selected as normal control group.The differences in serum levels of PCT,inflammatory factors and intestinal mucosal barrier function indexes were compared between the two groups,and Pearson test was used to evaluate the correlation between PCT content and severe acute pancreatitis.Results:Ser-um PCT content of pancreatitis group was higher than that of control group;serum IL-6,IL-10 and TNF-α contents were higher than those of control group;serum D-Lactate,DAO and Endotoxin contents were higher than those of control group. Pearson test showed that the serum PCT content of patients with severe acute pancreatitis was directly correlated with the de -gree of infection and intestinal mucosal barrier dysfunction.Conclusion:Serum PCT content abnormally increases in severe a-cute pancreatitis,and the specific content is directly correlated with the degree of infection and intestinal mucosal barrier dys-function.关键词
重症急性胰腺炎/降钙素原/炎症反应/肠黏膜屏障功能Key words
severe acute pancreatitis/procalcitonin/inflammatory response/intestinal mucosal barrier function分类
医药卫生引用本文复制引用
高静,陈曦,杨梅,张亚梅..重症急性胰腺炎血清降钙素原含量对感染程度、肠黏膜屏障功能的评估价值[J].海南医学院学报,2018,24(4):527-529,533,4.基金项目
四川省卫生计生委科技项目(17PJ380) This study was supported by the Science and Technology Project of Health and Family Planning Commission of Sichuan Province (17PJ380). （17PJ380）
