实用临床医药杂志2018,Vol.22Issue(5):71-73,3.DOI:10.7619/jcmp.201805022
榄香烯联合三维适形放疗治疗中晚期食管癌的临床观察
Elemene combined with three-dimensional conformal radiotherapy for treatment of advanced esophageal cancer
陈敬生 1金军 1陈永忠 1胡中保1
作者信息
- 1. 湖北省鄂州市中心医院肿瘤科,湖北鄂州,436000
- 折叠
摘要
Abstract
Objective To observe the short-term curative effect and toxicity reactions of elemene in combination with three-dimensional conformal radiotherapy for advanced esophageal cancer.Methods A total of 57 patients with advanced esophageal cancer were divided into radiotherapy group (28 cases) and elemene combined with radiotherapy group (29 cases).The control group was given conventional irradiation,and the treatment group received intravenous infusion of elemene on the basis of the control group.Changes of clinical symptoms were recorded.Results The effective rates in the control group and the treatment group were 60.7% and 75.9%,respectively,when follow-up at the 8th week after radiotherapy (P < 0.05).The patients of 2 groups were generally well tolerated,no grade Ⅳ toxicity occurred.Conclusion The efficacy of elemene combined with threedimensional conformal radiotherapy in the treatment of advanced esophageal cancer is better than radiotherapy alone,and it is safe and effective and had fewer side effects.关键词
中晚期食管癌/榄香烯/放疗/中医药疗法/毒副反应/Kaplan-Meier法Key words
advanced esophageal cancer/elemene/radiotherapy/Chinese medicinal therapy/toxicity effects/Kaplan-Meier method分类
医药卫生引用本文复制引用
陈敬生,金军,陈永忠,胡中保..榄香烯联合三维适形放疗治疗中晚期食管癌的临床观察[J].实用临床医药杂志,2018,22(5):71-73,3.