解放军医学院学报2017，Vol.38Issue(11)：1004-1008,5.DOI:10.3969/j.issn.2095-5227.2017.11.002
复杂区域疼痛综合征临床分析
Clinical characteristics of complex regional pain syndrome
钟艳艳 1张江林 1隋娜 1冀肖健 1孙飞 1廖思敏 1赵倩倩 1杨金水 1朱剑 1黄烽1
作者信息
摘要
Abstract
Objective To investigate the clinical characteristics and treatment of complex regional pain syndrome (CRPS).Methods Clinical data about 51 patients with complex regional pain syndrome admitted to our hospital from April 2000 to September 2016 were retrospectively analyzed.The patients were divided into different groups according to the disease course and gender,then the predisposing factors,concomitant disease,clinical manefestation and treatment for patients with CRPS were summarized.Results There were 22 cases (43.1％) with soft tissue injury history and 25 cases (49％) with sleep disorders.Pain was the chief complaint for all patients.Patients with short disease course (≤ 1 year) were prone to have limb dysfunction (x2=4.404,P=0.036),patients with joint of lower extremity (x2=10.667,P=0.001) and multi-sited (x2=32.980,P=0.000) involvement were more common seen.There were more female patients with osteoporosis than male patients (x2=4.554,P=0.033),while male patients were prone to have limb swelling (x2=5.368,P=0.026).CT was performed in 21 patients and 19 (91％) of them showed typical patchy osteoporosis and bone cyst degeneration.Patients who underwent bone scan (ECT) all showed lesion radioactivity,and 22 patients (43.1％) treated with bisphosphonates and 17 (33.3％) with hormone all achieved satisfactory pain relief.Conclusion CRPS is mainly caused by soft tissue injury,and middle-aged people are at high-risk.Joints of lower limbs are more likely to be involved.CT or ECT examination can guide clinical diagnosis,and steroids and bisphosphonates treatment are preferred therapies for patients with CRPS.关键词
复杂区域疼痛综合征/疼痛/骨质疏松Key words
complex regional pain syndrome/pain/osteoporosis分类
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钟艳艳,张江林,隋娜,冀肖健,孙飞,廖思敏,赵倩倩,杨金水,朱剑,黄烽..复杂区域疼痛综合征临床分析[J].解放军医学院学报,2017,38(11):1004-1008,5.
