摘要
Abstract
Objective To observe the clinical features in the elderly with diabetes type 2 complicated with hypertension.Methods 187 elderly patients in Liyuan Hospital during the period from Jan.,2016 to April,2017 were selected and divided into 2 groups:observation group (complicated with hypertension) and control group (with no hypertension);the levels of glycosylated hemoglobin (HbA1C),NT-proBNP,blood glucose,blood pressure and left ventricular function of the elderly in both groups were observed and a statistical study was made.Results The HbAlC level,fasting blood glucose,2h postprandial blood glucose,systolic blood pressure,diastolic blood pressure and the NT-proBNP level of the elderly in observation group were much higher than those of the elderly in control group (P＜0.05);the LVMI in observation group was obviously higher but LVEF and E/A were obviously lower than those in control group,and the differences were of statistical significance (P＜ 0.05);Pearson correlation analysis indicated that,in observation group,the level of HbAlC was in positive correlation with LVMI and NT-proBN (r=0.643,0.814,P＜0.05) but in negative correlation with LVEF and E/A (r=-0.582,-0.614,P＜0.05);NT-proBNP was in obvious correlation with LVMI and HbA1C (r=0.695,0.814,P＜0.05) but in obvious negative correlation with LVEF and E/A (r=-0.654,-0.688,P＜0.05);fasting blood glucose was positively correlated to LVMI,NT-proBNP (r=0.457,0.741,0.623,P＜0.05) but negatively correlated to LVEF and E/A (r=-0.372,-0.482,(P＜0.05);2h postprandial blood glucose was positively correlated to LVMI,HbAlC and NT-proBNP (r=0.508,0.809,0.704,P＜0.05) but negatively correlated to LVEF and E/A (r=-0.433,-0.405,P＜0.05).Conclusions The level of NT-proBNP is of higher predictive value of left ventricular hypertrophy of the elderly with diabetes complicated with hypertension;the level of HbAlC is in higher correlation with that of NT-proBNP;the detection is simple and easy in performance and wider application,and is expected to be used in left ventricular function screen in the elderly with diabetes complicated with hypertension.关键词
老年/糖尿病/高血压/左心室肥厚/糖化血红蛋白/N端前脑钠肽Key words
elderly/diabetes/hypertension/left ventricular hypertrophy/glycated hemoglobin/N terminal brain natriuretic peptide
