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血脂成分与冠状动脉病变狭窄程度的相关性研究

李洪璠 伍旭升 宋香静 杨海松 曹润红 宋泽星 段林林 王张生

老年医学与保健2017,Vol.23Issue(5):400-403,407,5.
老年医学与保健2017,Vol.23Issue(5):400-403,407,5.

血脂成分与冠状动脉病变狭窄程度的相关性研究

Correlation between Lipid Composition and the Severity of Coronary Artery Lesions

李洪璠 1伍旭升 2宋香静 1杨海松 1曹润红 1宋泽星 1段林林 1王张生3

作者信息

  • 1. 贵州省瓮安县人民医院心内科,瓮安县550400
  • 2. 上海交通大学医学院附属上海市同仁医院心内科,上海200336
  • 3. 复旦大学附属第五人民医院心内科,上海200240
  • 折叠

摘要

Abstract

Objective To explore the correlation between the lipid composition and the severity of coronary artery lesions.Methods Coronary angiography was made to 511 suspected coronary artery disease in-patients with repeated occurrence of chest distress and chest pain,and Gensini score was applied in estimating the severity of coronary artery lesions,the scores,as well as the lipid compositions,other blood biochemical indicators and risk factors were statistically analyzed.Results Patients with different Gensini scores had different HDL (P< 0.01),LDL/HDL (P=0.004),TG/HDL (P=0.027) and NHDL/ apoB (P=0.044),the difference was of statistical significance;multiple linear regression analysis showed that apoB/LDL-C (P<0.001),cTnT (P<0.01) and LDL-C/HDL-C (P=0.008) were closely correlated to the severity of coronary artery lesions.Conclusions The severity of coronary artery lesion is correlated to dyslipidemia and apoB/LDL-C might be superior in predicating coronary heart disease to other lipid indicators and lipid compositions.

关键词

血脂成分/载脂蛋白B/冠状动脉粥样硬化性心脏病/Gensini积分

Key words

lipid composition/apolipoprotein B/coronary heart disease/Gensini score

引用本文复制引用

李洪璠,伍旭升,宋香静,杨海松,曹润红,宋泽星,段林林,王张生..血脂成分与冠状动脉病变狭窄程度的相关性研究[J].老年医学与保健,2017,23(5):400-403,407,5.

老年医学与保健

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