中南医学科学杂志2018，Vol.46Issue(1)：37-41,78,6.DOI:10.15972/j.cnki.43-1509/r.2018.01.009
可控应力轴向诱导山羊腰椎间盘退变的实验研究
Experiment Research of goat's lumbar disc degeneration induced axially by controllable stress
摘要
Abstract
To discuss the feasibility of the controllable stress device,which is created independently,inducing the goat's lumbar disc degeneration by forcing axially,and observe the imaging manifestations.16 goats were chosen and ran-domly divided into pressure and control groups(every group,n=8).The device was fixed on the lumbar 4 and 5 of the goats by percutaneous puncture and compress the L4/5 disc.The force of compression was set as 40N the pressure group,and in the control group was 0N.At the time of the 4th and 8th week,all goats underwent the X-Ray and MRI examination.At 4th week,in the pressure group,6 goats were Pfirrmann level 3,2 goats were Pfirrmann level 2,and all the goats in control group was level 1.At 8th week,the DHI of pressure group was much less than control group(P<0.05).Among the pressure group, 5 goats was Pfirrmann level 4,3 goats were Pfirrmann level 3,and all the goats in control group was level 1.According to the results,it is feasible that using the controllable stress device could induce the goat's lumbar disc degeneration.The longer compression last by the same controllable force,the more obvious changes in imaging.关键词
可控应力/轴向压缩/椎间盘退变/实验研究Key words
controllable pressure/axial induce/intervertebral disc degeneration/experiment research分类
医药卫生引用本文复制引用
宋西正,康禹,胡磊,舒小林,曹鑫,易明,彭文,王文军..可控应力轴向诱导山羊腰椎间盘退变的实验研究[J].中南医学科学杂志,2018,46(1):37-41,78,6.基金项目
国家自然基金面上项目(No.81272055/H612). （No.81272055/H612）
