世界中医药2017，Vol.12Issue(10)：2326-2329,4.DOI:10.3969/j.issn.1673-7202.2017.10.014
丹红注射液治疗短暂性脑缺血发作的疗效分析及对患者血流动力学及神经功能的影响
Therapeutic Effects Analysis of Danhong Injection in Treating Transient Ischemic Attack and Influence on Patient's Hemodynamics and Neurological Function
摘要
Abstract
Objective:To investigate the therapeutic effects of Danhong Injection in treating transient ischemic attack (TIA) and the influence on patient's hemodynamics,neurological function and other blood biochemical indexes.Methods:A total of 86 patients with TIA who were admitted and treated in our hospital were randomly divided into treatment group and control group with 43 patients in each group.The control group received conventional western medicine treatment,and the treatment group was added Danhong Injection.Both groups were treated continuously for 14 d,with at least 3 months' follow-up visit after treatment.The therapeutic effects of 2 groups were evaluated,and the changes of hemodynamics,neurological function and other blood biochemical indexes were detected and compared.Results:The Vmean,Vmax,Vmin,Qmean of two groups were increased compared with that before treatment,and R was significantly decreased (P ＜ 0.05 or P ＜ 0.01).The difference between 2 groups was significant (P ＜ 0.05 or P ＜ 0.01).The neurological function indexes levels of serum S-100B,GFAP,NSE,MBP,and Cys-c,Hcy,CD62p,CD63 were significantly decreased compared with that before treatment (P ＜0.05 or P ＜0.01),and the treatment group was significantly low-er than the control group (P ＜ 0.05 or P ＜ 0.01).The recurrence rate and incidence rate of cerebral infarction in treatment group were 11.63％ and 6.98％,which was lower than 34.88％ and 25.58％ in control group (P ＜ 0.05).Conclusion:Danhong Injection in treating TIA has low recurrence rate and low incidence rate of cerebral infraction,and can significantly improve hemodynamics and accelerate cerebral blood flows,as well as effectively inhibit hematoblastic activation function to further improve the recovery of patient's neurological function.关键词
短暂性脑缺血发作/丹红注射液/血流动力学/神经功能/血生化Key words
Transient ischemic attack/Danhong injection/Hemodynamics/Nerve function/Blood biochemistry分类
医药卫生引用本文复制引用
曹樱花..丹红注射液治疗短暂性脑缺血发作的疗效分析及对患者血流动力学及神经功能的影响[J].世界中医药,2017,12(10):2326-2329,4.基金项目
2016～2017河北省医学适用技术跟踪项目(GL201649) （GL201649）
