实用医学杂志2018，Vol.34Issue(2)：273-276,4.DOI:10.3969/j.issn.1006-5725.2018.02.029
高通量血液透析联合尿毒清对老年终末期肾病患者细胞免疫的影响
Effect of high fluxes of hemodialysis combined with Niaoduqing granuleson on cell-mediated immunity in old patients
摘要
Abstract
Objective To investigate the effect of high fluxes of hemodialysis combined with Niaoduqing granuleson in the cell-mediated immunity of elderly hemodialysis patients. Methods Fourty cases of elderly main-tenance hemodialysis patients with end-stage renal disease were randomly divided into control group and treatment group,low flux dialysis was used in both groups before the experiment,in the experiment control group adopts high flux hemodialysis,the treatment group in the control group on the basis of daily oral Niaoduqing granules 5 g, 3 times/d,observation for 3 months,compare the serum IL-2,IL-10,CD3+,CD4+,CD8+,CD4+/CD8+change of the two groups in 3 months.Results After 3 months high flux dialysis treatment,the level of IL-2 was significant-ly increased before the treatment of low flux dialysis,and the level of IL-10 was significantly reduced.The levels of IL-2 and IL-10 were significantly higher in the treatment group than in the control group after 3 months(P <0.01);The CD3+,CD4+and CD4+/CD8+levels of the two groups of high flux dialysis were significantly higher than that in the previous three months(P<0.05).The levels of IL-2,IL-10,CD3+,CD4+,CD4+/CD8+were significantly higher in the treatment group after 3 months than the control group(P<0.05).Conclusion High fluxes of hemo-dialysis can improve the immune function of elderly hemodialysis patients,while combined with Niaoduqing gran-ules is more obvious.关键词
血液透析/终末期肾病/高通量透析/尿毒清/细胞免疫Key words
hemodialysis/elderly hemodialysis patients/high fluxes of hemodialysis/cell-mediated immunity引用本文复制引用
张洪源,林小堃..高通量血液透析联合尿毒清对老年终末期肾病患者细胞免疫的影响[J].实用医学杂志,2018,34(2):273-276,4.基金项目
广东省佛山市科技局市级医学类科技攻关项目(编号:2016AB001082) （编号:2016AB001082）
