天津中医药2018，Vol.35Issue(2)：97-100,4.DOI:10.11656/j.issn.1672-1519.2018.02.06
化浊解毒方联合二甲双胍对2型糖尿病患者LPL影响
Clinical observation of removing turbidity and detoxication decoction combined with metformin effect on lipoprotein lipase in patients with type 2 diabetes
摘要
Abstract
[Objective]To observe the effect of removing turbidity and detoxication decoction combined with metformin on Lipoprotein lipase in patients with type 2 diabetes. [Methods] The 100 Patients were screened with type 2 diabetes who belong to turbidity and detoxication intrinsic type,and divided into treatment group and control group randomly.The treatment group added removing turbidity and detoxication decoction on basis of conventional treatment. Clinical symptoms and signs were evaluate, also the change of triglycerides,total cholesterol,high density lipoprotein cholesterol, low density lipoprotein cholesterol, free fatty acids, and lipoprotein lipase after 8 weeks were detected. [Results]In the course of the study,9 cases were lost,and 91 cases were completed,of which 44 cases in the treatment group and 47 cases in the control group.The two groups showed no difference before treatment.After treatment,the clinical symptoms and signs of the treatment group were significantly improved compared with the control group,the levels of serum TG, TC, LDL, FFA were significantly decreased in the treatment group, LPL level was significantly increased, compared with the control group,the difference was statistically significant. [Conclusion]Detoxication decoction may increase the level of serum LPL to affect the lipid metabolism of patients,in order to improve the level of blood lipid in type 2 diabetic patients and relieve the clinical symptoms and signs.关键词
化浊解毒方/2型糖尿病/脂蛋白脂酶/浊毒Key words
detoxication decoction/type 2 diabetes/lipoprotein lipase/turbid分类
医药卫生引用本文复制引用
王斌,刘洁,王英月,曹红波..化浊解毒方联合二甲双胍对2型糖尿病患者LPL影响[J].天津中医药,2018,35(2):97-100,4.基金项目
国家自然科学基金青年基金项目(81102578) （81102578）
天津市131第二层次人才资助项目(zx160123). （zx160123）
