天津中医药大学学报2018，Vol.37Issue(1)：1-5,5.DOI:10.11656/j.issn.1673-9043.2018.01.01
冠心病痰瘀互结病机及生物学基础研究概述
An overview of pathogenesis and biological basis in phlegm and blood stasis of coronary heart disease
摘要
Abstract
In recent years, due to the high morbidity and serious lesion of intermin-gled phlegm and blood stasis syndrome of CHD, people are paying more attention to it. By reading the literature, we reviewed the possible biological basis of phlegm stasis syndrome from etiology, pathogenesis, lipid metabolism, inflammatory mediators, homocysteine and gene polymorphism. Preliminary studies determined that the formation of intermin-gled phlegm and blood stasis syndrome including yin and yang deficiency,spleen-stomach transportation-metabolism disability, liver dysfunction,the stagnation of phlegm turbidity and retained fluid.AS is the result of interaction of many factors, and is one of the pathological bases for the formation of CHD,AS and myocardial ischemia are particularly likely to show pathological factors such as phlegm turbidity and congestion.This article will overview the pathogenesis and biological basis of intermin-gled phlegm and blood stasis syndrome from traditional Chinese medicine and western medicine,so as to provide guidance for clinical syndrome differentiation.关键词
痰瘀互结/动脉粥样硬化/脂质代谢/炎症介质/多态性Key words
intermin-gled phlegm and blood stasis/atherosclerosis/lipid metabolism/inflammation mediators/polymorphism分类
医药卫生引用本文复制引用
闫丹丹,边育红,于春泉..冠心病痰瘀互结病机及生物学基础研究概述[J].天津中医药大学学报,2018,37(1):1-5,5.基金项目
国家重点基础研究发展计划(973计划)项目(2014CB542902). （973计划）
