补肾健脾法影响PCOS-IR先兆流产者血清pAkt、mTOR的研究OACSTPCD
Effect of the tonifying kidney and invigorating spleen on serum pAkt and mTOR in patients with threatened abortion of polycystic ovary syndrome in insulin resistance
[目的]观察补肾健脾法对 多囊卵巢综合征胰岛素抵抗(PCOS-IR)先兆流产患者的临床疗效,进一步探讨其机制.[方法]酶联免疫吸附测定(ELISA)法检测PCOS先兆流产者中药治疗前后及 健康妇女血清激素水平[孕酮(P)、特异性人绒毛促性腺激素(β-HCG)]、HOMA-IR、pAkt和mTOR的表达变化.[结果]治疗前:PCOS-IR先兆流产者(A组)、PCOS非胰岛素抵抗(PCOS-NIR)先兆流产者(B组)和健康妊娠妇女(C组)相比,pAk…查看全部>>
[Objective]To observe the clinical efficacy of the use of tonifying kidney and invigorating spleen on Polycystic ovary syndrome in insulin resistance(PCOS-IR)patients with threatened abortion,and to further explore its mechanism. [Methods]Elisa method was used to detect the changes of serum hormone(progesterone(P)and human chorionic gonadotropin(β-HCG)),pAkt and mTOR in Polycystic ovary syndrome patients with threatened abortion and healthy pregnant women be…查看全部>>
蒋莎;姜俊竹;陈璐;冯晓玲
黑龙江中医药大学,哈尔滨150040黑龙江中医药大学,哈尔滨150040黑龙江中医药大学附属第一医院,哈尔滨150040黑龙江中医药大学附属第一医院,哈尔滨150040
医药卫生
补肾健脾法多囊卵巢综合征胰岛素抵抗高胰岛素血症活化Akt哺乳动物雷帕霉素靶蛋白
the method of tonifying the kidney and strengthening the spleenpolycystic ovary syndrome with insulin resistancehyperinsulinemiapAktmTOR
《天津中医药大学学报》 2018 (1)
28-32,5
国家中医药管理局国家中医临床研究基地业务建设科研专项课题(JDZX2012042).
评论