天津中医药大学学报2018，Vol.37Issue(1)：58-60,3.DOI:10.11656/j.issn.1673-9043.2018.01.14
五味降压散镇痛镇静作用的实验研究
Experimental study on the analgesic and sedative effects of Wuwei Jiangya formula
摘要
Abstract
[Objective]To study the analgesic and sedative effects of Wuwei Jiangya formula. [Methods]Writhing method and heat stimulation method were used to observe the analgesic effect.Tail-hanging test was used to observe the sedative effect of Wuwei Jiangya formula on mice. [Results]The results showed that Wuwei Jiangya formula at medium dose could significantly reduce writhing times of mice. Low dose treatment for 90 min and high dose treatment for 30 min and 90 min could significantly increase mice pain thresholds.Meanwhile,high dose for 120 min extended 5 min tail-hanging immobility time of mice.[Conclusion]Certain dose of Wuwei Jiangya formula may play a role in analgesia and sedation.关键词
五味降压散/镇痛/镇静Key words
Wuwei Jiangya formula/analgesic/sedative分类
医药卫生引用本文复制引用
李雪丽,王伟,王佩佩,弓铭,邓冬,李韶菁,任莹璐,马雪玲,赵慧辉..五味降压散镇痛镇静作用的实验研究[J].天津中医药大学学报,2018,37(1):58-60,3.基金项目
国家自然科学基金项目(81473521,81102730) （81473521,81102730）
北京中医药大学创新团队项目(2011-CXTD-06) （2011-CXTD-06）
北京市支持中央在京高校共建项目(0101186) （0101186）
国家自然科学基金青年项目(81503382) （81503382）
北京中医药大学中青年教师项目(2015-JYB-JSMS036). （2015-JYB-JSMS036）
