天津中医药大学学报2018,Vol.37Issue(1):84-88,5.DOI:10.11656/j.issn.1673-9043.2018.01.20
间充质干细胞移植治疗骨质疏松研究进展
The research progress about MSCs transplant of osteoporosis
摘要
Abstract
Until now anti-osteoporosis drug researches mainly focus on the balance about bone resorption with formation, while little research about the relation about MSCs number and function(migration, homing, differentiation)with osteoporosis. Osteoblast and adipocyte both derived from MSCs,therefore when MSCs is impaired,which resulting that osteoblasts function decreases, and adipocyte number increases, and the bone mass losses,finally caused osteoporosis.MSCs transplant could increase bone mass and density,and it would became new methods to cure osteoporosis.关键词
骨质疏松/间充质干细胞/移植治疗Key words
osteoporosis/MSCs/transplantation分类
医药卫生引用本文复制引用
艾菊青,毛浩萍..间充质干细胞移植治疗骨质疏松研究进展[J].天津中医药大学学报,2018,37(1):84-88,5.基金项目
国家自然科学基金项目(81303247). (81303247)