云南农业大学学报（自然科学）2017，Vol.32Issue(6)：1129-1133,5.DOI:10.16211/j.issn.1004-390X(n).2017.06.023
绿茶饮增强小鼠的嗅觉记忆和短时空间记忆
Green Tea Extract Improves Olfactory Memory and Short-term Spatial Memory in Mice
摘要
Abstract
[Purpose] To provide new ideas for the health-care function of green tea,the effect of green tea extract (GTE) on olfactory memory and short-term spatial memory were investigated in mice.[Method] The GTE group and the control group were orally administrated 2％ GTE or pure water for 12 weeks.Odor discrimination apparatus were used to test the olfactory memory,and the inter-trail interval (ITI) were 40 or 80 min.Y-maze apparatus were used to test the short-term spatial memory,and the ITI were 1,2,or 4 h.[Results] At 80 min ITI,GTE-treated mice,not the control mice,retained a memory of the odor that had been previously presented (P ＜ 0.05).At 4h ITI,GTE-treated mice showed significantly higher percentage of novel arm time than other two arms (P ＜ 0.01),and the percentage of novel arm time of GTE group was significantly higher than the control group (P ＜0.05).[Conclusion] Olfactory memory and short-term spatial memory were improved by long-term administration of GTE in mice,which suggested that green tea may be used for the prevention and treatment of olfactory disorder related diseases.关键词
绿茶/嗅觉记忆/短时空间记忆/小鼠Key words
green tea/olfactory memory/short-term spatial memory/mouse分类
医药卫生引用本文复制引用
刘慧浪,苏敏,杨建珍,白帆,王京昆..绿茶饮增强小鼠的嗅觉记忆和短时空间记忆[J].云南农业大学学报（自然科学）,2017,32(6):1129-1133,5.基金项目
国家自然科学基金项目(31271168). （31271168）
