帕瑞昔布钠超前镇痛用于内镜黏膜下剥离术的安全性和有效性OA北大核心CSTPCD
Effect and Safety of Paracoxib Sodium on Preemptive Analgesia by Endoscopic Submucosal Dissection
目的 观察帕瑞昔布钠用于内镜黏膜下剥离手术的安全性和有效性.方法 选取拟行内镜黏膜下剥离术的患者80例,随机分为对照组(0.9%氯化钠溶液组)和帕瑞昔布钠组,各40例.分别于麻醉诱导前10 min静脉注射0.9%氯化钠注射液5 mL或帕瑞昔布钠40 mg+0.9%氯化钠注射液5 mL,术毕两组患者均给予盐酸托烷司琼2 mg和地佐辛5 mg.于帕瑞昔布钠或0.9%氯化钠溶液用药前、用药后30及120 min时采集静脉血检测凝血功能,并记录苏醒即刻,…查看全部>>
Objective To investigate the preemptive analgesic effect and safety of paracoxib sodium in patients under-going endoscopic submucosal dissection(ESD). Methods A total of 80 ASA I or II patients aged 35-65 years undergoing ESD under general anesthesia were randomized into two groups(n=40 each):parecoxib sodium group(group B) was received intrave-nous parecoxib sodium 40 mg (in 5 mL 0.9% sodium chloride solution) 10 min before anesthesia induction and control …查看全部>>
刘尚昆;徐卉
华中科技大学同济医学院附属同济医院麻醉科,武汉 430030华中科技大学同济医学院附属同济医院麻醉科,武汉 430030
医药卫生
帕瑞昔布钠剥离术,内镜黏膜下超前镇痛
Parecoxib sodiumDissection,endoscopic submucosalPreemptive analgesia
《医药导报》 2018 (3)
329-332,4
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