中风与神经疾病杂志2018，Vol.35Issue(2)：145-148,4.
妊娠相关可逆性后部脑病综合征36例临床分析
Clinical analysis of 36 patients with pregnancy-related PRES
摘要
Abstract
Objective To investigate the clinical and radiologic features of pregnancy-related posterior reversible en-cephalopathy syndrome (PRES).Methods To search all imaged patients with preeclampsia/eclampsia/PRES in our hos-pital,then we select pregnancy-related PRES and summarize clinical and radiologic findings together with treatment.Results A total of 36 patients were eventually included as confirmed pregnancy-related PRES.Of 28 eclamptics,26 eclamptics (92%) had confirmed PRES.Headache was the most common presenting symptom (81%) followed by seizures (73%), altered mental status (57%),nausea/vomiting (47%) and visual disturbance(33%).Atypical involved regions included frontal lobe (72%),temporal lobe (67%),basal ganglia (50%),cerebellum (47%),brain stem (14%) and thalamus (8%).Typical imaging findings of PRES were reversible vasogenic edema mainly located in bilateral parieto-occipital areas and subcortical white matter. Atypical neuroimaging features included restricted diffusion (33%),contrast enhancement (19%) and hemorrhage (19%).Comorbidities included thrombocytopenia (25%),pulmonary infection (25%),anemia (19%),fever (17%),acute renal failure (8%),HELLP syndrome (6%),DIC (3%).Most of patients recovered com-pletely with timely diagnosis and treatment.1 patients who suffered DIC eventually died.Conclusion Nearly all eclamptic patients who underwent imaging had clinical and radiologic findings of PRES;Patients with pregnancy-related PRES may present with atypical neuroimaging findings.关键词
妊娠/可逆性后部脑病综合征/磁共振Key words
Pregnancy/Posterior reversible encephalopathy syndrome/Magnetic resonance imaging分类
医药卫生引用本文复制引用
阳柏凤,文延斌,刘运海,曹红桂,雷达,李静..妊娠相关可逆性后部脑病综合征36例临床分析[J].中风与神经疾病杂志,2018,35(2):145-148,4.基金项目
国家临床重点专科建设项目[国卫办医函(2013)544号] （2013）
国家自然科学基金资助项目(81471225) （81471225）
