中国动脉硬化杂志2018，Vol.26Issue(1)：73-76,108,5.
25羟维生素D及甲状旁腺激素与高血压的关系
The relationship between 25 hydroxyvitamin D, parathyroid hormone levels and hypertension
付鹏 1张琳 2杨博逸 1牛铁生1
作者信息
- 1. 中国医科大学附属盛京医院心血管内科,辽宁省沈阳市110000
- 2. 树兰(杭州)医院心血管内科,浙江省杭州市310000
- 折叠
摘要
Abstract
Aim To explore the direct correlation between serum levels of 25-hydroxyvitamin D [25-(OH) D],parathyroid hormone (PTH) and hypertension.Methods From March 2014 to July 2015,368 patients inhospitalized in department of cardiology were selected.Based on the presence of hypertension,they were divided into hypertension group (198 cases) and non-hypertension group (170 cases).Demographic information was collected and blood samples were taken to probe levels of PTH and 25-(OH) D.Correlation between 25-(OH) D,PTH and hypertension were tested.Results Serum 25-(OH) D level of patients in hypertension group was lower than that in non-hypertension group (37.67± 18.23 nmol/L vs 42.45±20.41 nmol/L,P=0.018).Difference in PTH of the two groups lacked statistical significance (50.08±28.80 ng/L vs 50.45±22.37 ng/L,P=0.892).Pearson correlation analysis showed that 25-(OH)D level was negatively correlated with PTH(r=-0.225,P＜0.05).Multivariable logistic regression indicated that vitamin D deficiency was the independent risk factor of hypertension (OR =1.847,95％ CI 1.138 ～ 2.996,P =0.013),whereas PTH showed no correlation with hypertension.Conclusion Vitamin D lack or deficiency has independent risk effect on hypertension.关键词
高血压/血清25羟维生素D/甲状旁腺激素Key words
Hypertension/Serum 25-hydroxyvitamin D/Parathyroid hormone分类
医药卫生引用本文复制引用
付鹏,张琳,杨博逸,牛铁生..25羟维生素D及甲状旁腺激素与高血压的关系[J].中国动脉硬化杂志,2018,26(1):73-76,108,5.
