中国动脉硬化杂志2018,Vol.26Issue(1):91-98,8.
新生滋养血管在动脉粥样硬化形成中的作用及临床意义
Vasa vasorum in pathological process of atherosclerosis and clinical significance
摘要
Abstract
The main clinical risk of atherosclerotic (As) lesions is the instability and vulnerability of plaques.Vasa vasorum (VV) inside the As plaque has structural defects,such as fragile and high leakage of vascular wall.These structural defects lead to plaque rupture and hemorrhage,which promotes inflammatory response,provides channel for leukocyte and blood soluble components entering the plaque and promotes As plaque formation.VV inside the As plaque is closely related to plaque rupture and hemorrhage,and clinical cardiovascular events.Intensive study of the VV function and its related signaling pathway in As is expected to fundamentally prevent As plaque development.关键词
动脉粥样硬化/滋养血管/血管新生/血管成熟化Key words
Atherosclerosis/Vasa vasorum/Neovascularization/Vascular maturation分类
医药卫生引用本文复制引用
李萌,张军平,朱科,漆仲文,邹升..新生滋养血管在动脉粥样硬化形成中的作用及临床意义[J].中国动脉硬化杂志,2018,26(1):91-98,8.基金项目
国家自然科学基金项目(81473634) (81473634)