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新生滋养血管在动脉粥样硬化形成中的作用及临床意义

李萌 张军平 朱科 漆仲文 邹升

中国动脉硬化杂志2018,Vol.26Issue(1):91-98,8.
中国动脉硬化杂志2018,Vol.26Issue(1):91-98,8.

新生滋养血管在动脉粥样硬化形成中的作用及临床意义

Vasa vasorum in pathological process of atherosclerosis and clinical significance

李萌 1张军平 1朱科 2漆仲文 2邹升2

作者信息

  • 1. 天津中医药大学第一附属医院,天津市300193
  • 2. 天津中医药大学研究生院,天津市300193
  • 折叠

摘要

Abstract

The main clinical risk of atherosclerotic (As) lesions is the instability and vulnerability of plaques.Vasa vasorum (VV) inside the As plaque has structural defects,such as fragile and high leakage of vascular wall.These structural defects lead to plaque rupture and hemorrhage,which promotes inflammatory response,provides channel for leukocyte and blood soluble components entering the plaque and promotes As plaque formation.VV inside the As plaque is closely related to plaque rupture and hemorrhage,and clinical cardiovascular events.Intensive study of the VV function and its related signaling pathway in As is expected to fundamentally prevent As plaque development.

关键词

动脉粥样硬化/滋养血管/血管新生/血管成熟化

Key words

Atherosclerosis/Vasa vasorum/Neovascularization/Vascular maturation

分类

医药卫生

引用本文复制引用

李萌,张军平,朱科,漆仲文,邹升..新生滋养血管在动脉粥样硬化形成中的作用及临床意义[J].中国动脉硬化杂志,2018,26(1):91-98,8.

基金项目

国家自然科学基金项目(81473634) (81473634)

中国动脉硬化杂志

OACSTPCD

1007-3949

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