中国动脉硬化杂志2018，Vol.26Issue(1)：103-108,6.
脂质代谢相关microRNA概述
Overview of lipid metabolism related microRNA
徐将 1陈露 1王小洪 1张新江 2梁景岩1
作者信息
- 1. 扬州大学解剖学教研室
- 2. 扬州市第一人民医院神经内科,江苏省扬州市225000
- 折叠
摘要
Abstract
MicroRNA is an important regulatory factor in the process of gene expression,which plays a very important role in cell differentiation,proliferation,apoptosis and lipid metabolism.Research on microRNA and lipid metabolism has been a hotspot in recent years.The microRNA-33,microRNA-122,microRNA-370,microRNA-758,microRNA-27,microRNA-30c,microRNA-223 and microRNA-144 were mainly involved in the microRNAs related to lipid metabolism.Among them,microRNA-122 and microRNA-33 play a major role in regulating cholesterol and fatty acid balance in vivo.MicroRNAs are involved in the regulation of cell differentiation and lipid metabolism.They are also regulated by transcription factors,adipoc ytokines and environmental factors.Different microRNAs form a complex regulatory network through the regulation of target gene mRNA.This paper reviews the role and the way of microRNA regulation of lipid metabolism.关键词
microRNA/脂质代谢/调控因子Key words
MicroRNA/Lipid metabolism/Regulatory factor分类
生物科学引用本文复制引用
徐将,陈露,王小洪,张新江,梁景岩..脂质代谢相关microRNA概述[J].中国动脉硬化杂志,2018,26(1):103-108,6.
