中国肺癌杂志2018,Vol.21Issue(2):129-138,10.DOI:10.3779/j.issn.1009-3419.2018.02.07
Pan-negative型非小细胞肺癌的研究进展
Research Advances of Pan-negative Type of Non-small Cell Lung Cancer
孙丽 1熊志成 1韩琤波1
作者信息
- 1. 110022 沈阳,中国医科大学盛京医院肿瘤内科
- 折叠
摘要
Abstract
In recent years,series of driver genes,such as EGFR,KRAS/NRAS,BRAF,PIK3CA,ALK and ROS1 and so on, have been found in non-small cell lung cancer (NSCLC) one after another with the development of molecular detect-ing technology. Targeted drugs bring benefits for these NSCLC patients with driver gene variations. However, some NSCLC did not have any known driver gene variations; we called it pan-negative lung cancer. In this paper, we summarize the concept, clinical pathological characteristics, the epidemiological characteristics, treatment and prognosis of pan-negative NSCLC.关键词
肺肿瘤/驱动基因/Pan-negativeKey words
Lung neoplasms/Driver gene/Pan-negative引用本文复制引用
孙丽,熊志成,韩琤波..Pan-negative型非小细胞肺癌的研究进展[J].中国肺癌杂志,2018,21(2):129-138,10.