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Pan-negative型非小细胞肺癌的研究进展

孙丽 熊志成 韩琤波

中国肺癌杂志2018,Vol.21Issue(2):129-138,10.
中国肺癌杂志2018,Vol.21Issue(2):129-138,10.DOI:10.3779/j.issn.1009-3419.2018.02.07

Pan-negative型非小细胞肺癌的研究进展

Research Advances of Pan-negative Type of Non-small Cell Lung Cancer

孙丽 1熊志成 1韩琤波1

作者信息

  • 1. 110022 沈阳,中国医科大学盛京医院肿瘤内科
  • 折叠

摘要

Abstract

In recent years,series of driver genes,such as EGFR,KRAS/NRAS,BRAF,PIK3CA,ALK and ROS1 and so on, have been found in non-small cell lung cancer (NSCLC) one after another with the development of molecular detect-ing technology. Targeted drugs bring benefits for these NSCLC patients with driver gene variations. However, some NSCLC did not have any known driver gene variations; we called it pan-negative lung cancer. In this paper, we summarize the concept, clinical pathological characteristics, the epidemiological characteristics, treatment and prognosis of pan-negative NSCLC.

关键词

肺肿瘤/驱动基因/Pan-negative

Key words

Lung neoplasms/Driver gene/Pan-negative

引用本文复制引用

孙丽,熊志成,韩琤波..Pan-negative型非小细胞肺癌的研究进展[J].中国肺癌杂志,2018,21(2):129-138,10.

中国肺癌杂志

OA北大核心CSCDCSTPCDMEDLINE

1009-3419

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