中国感染控制杂志2017，Vol.16Issue(12)：1116-1119,4.DOI:10.3969/j.issn.1671-9638.2017.12.003
五种常用消毒剂对金黄色葡萄球菌的杀灭效果评价
Bactericidal efficacy of five kinds of disinfectant on Staphylococcus aureus
摘要
Abstract
Objective To study the bactericidal efficacy of hospital commonly used disinfectants such as ethanol,3" chlorine tablets,iodophor,glutaraldehyde,and avagard instant hand antiseptic on Staphylococcus aureus (S.a ureus) from different sources of hospital,and provide scientific basis for effective control of healthcare-associated infection(HAI).Methods A total of 48 strains of S.aureus from inpatients,hands of health care workers,and environment surface in the First Affiliated Hospital of Nanchang University were collected.Disinfectant was directly contacted with bacteria,in vitro killing efficacy of disinfectant on S.aureus from different sources at different diluted concentrations,and different contact time were studied.Results The killing rate of 5g/L iodophor,20g/L glutaraldehyde,and avagard instant hand antiseptic(0.5％ chlorhexidine + 70％ ethanol) to S.aureus with a 5-minute contact time was 100％;killing rates of 70％ ethanol and 1g/L 3" chlorine tablets to S.aureus with a 5-minute contact time were 96.5 ％-99.8 ％;but highly diluted iodophor,glutaraldehyde,and avagard instant hand antiseptic still could not completely kill S.aureus even the contact time was extended.Conclusion The routine use of disinfectants in the hospital can meet the clinical bactericidal efficacy,it is necessary to monitor concentration routinely,avoid decreasing sterilization ability.关键词
金黄色葡萄球菌/消毒剂/杀菌作用Key words
Staphylococcus aureus/disinfectant/bactericidal efficacy分类
医药卫生引用本文复制引用
董霞,李培群,罗东,刘涛,万腊根,陈开森..五种常用消毒剂对金黄色葡萄球菌的杀灭效果评价[J].中国感染控制杂志,2017,16(12):1116-1119,4.基金项目
国家自然科学基金资助项目(81660555) （81660555）
南昌大学大学生科技创新基金(2016213) （2016213）
