中国临床医学2017，Vol.24Issue(5)：690-695,6.DOI:10.12025/j.issn.1008-6358.2017.20170494
应用实时三维超声心动图评价房间隔缺损介入封堵术前后左心室收缩同步性
Real-time three-dimensional echocardiography in evaluating left ventricular systolic synchrony in patients with atrial septal defect before and after interventional occlusion
摘要
Abstract
Objective:To investigate the dynamic change of left ventricular systolic synchrony in patients with atrial septal defect (ASD) before and after interventional occlusion using real-time three-dimensional echocardiography (RT-3DE).Methods:A total of 52 patients undergoing interventional occlusion in Zhongshan Hospital from September 2015 to January 2016 were enrolled in this study.All subjects were assigned to take RT-3DE one day before,one day and one month after the interventional occlusion.TomTec 4D LV-Analysis CRT 1.0 software was used to analyze volume-time curves (VTC) of the 16 segments of the left ventricle.Parameters including time to minimal segmental volume (Tmsv),time to minimal segmental volume-standard deviation (Tmsv16-SD),and time to minimal segmental volume-difference (Tmsv16-Dif) were analysed.These three parameters were standardized by dividing cardiac cycle to generate other three parameters:Tmsv％,Tmsv16 SD％,and Tmsv16-Dif％.Results:VTC before the interventional occlusion suggested dyssynchronation of the left ventricular systole;VTC of one day after the interventional occlusion suggested synchronization of the left ventricle.So did the results of one month after the interventional occlusion.Accordingly,parameters including Tmsv,Tmsv％,Tmsv16 SD,Tmsv16-SD％,Tmsv16-Dif,and Tmsv16-Dif％ were significantly improved one day after occlusion as compared with one day before occlusion.These parameters were not significantly changed one month after occlusion as compared with one day after occlusion.In terms of the contraction amplitude,only a few segments showed a significant improvement one day after the interventional occlusion,most segments did not improve until one month later.Conclusions:Interventional occlusion significantly improved left ventricular systolic synchronization in patients with ASD one day after occlusion.Additionally,the contraction amplitude was significantly improved one month after the interventional occlusion.关键词
实时三维超声心动图/左心室收缩同步性/介入封堵术Key words
real-time three-dimensional echocardiography/left ventricular systolic synchronization/interventional occlusion分类
医药卫生引用本文复制引用
周怡,左武旭,潘翠珍,葛均波..应用实时三维超声心动图评价房间隔缺损介入封堵术前后左心室收缩同步性[J].中国临床医学,2017,24(5):690-695,6.基金项目
新疆维吾尔自治区自然科学基金(2015211C230).Supported by Natural Science Foundation of the Xinjiang Uygur Autonomous Region of China (2015211C230). （2015211C230）
