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妊娠期宫颈液基细胞学检查异常孕妇产后的临床转归

许颖 李柱南 陈忆 欧阳婧 李冬 吴丹

中国临床医学2017,Vol.24Issue(5):701-704,4.
中国临床医学2017,Vol.24Issue(5):701-704,4.DOI:10.12025/j.issn.1008-6358.2017.20170403

妊娠期宫颈液基细胞学检查异常孕妇产后的临床转归

Postpartum prognosis of women with cervical cytology abnormality during gestation

许颖 1李柱南 1陈忆 1欧阳婧 1李冬 1吴丹1

作者信息

  • 1. 上海交通大学医学院附属国际和平妇幼保健院宫颈科,上海200030
  • 折叠

摘要

Abstract

Objective:To study the postpartum prognosis of pregnant women with abnormal cervical cytology during gestation so as to provide evidence for clinical diagnosis and treatment of abnormal cervical cytology during gestation.Methods:A retrospective analysis was done on 534 pregnant women with thinprep cytological test(TCT)≥ASC-US.The results of TCT examination and the infection rate of high-risk human papilloma virus (HPV) were compared between gestation and 8 weeks postpartum.Results:Among the 534 pregnant women,425 cases (79.59%) were atypical cells,105 cases were low-grade squamous intraepithelial lesions (LSIL,19.66 %),and 4 cases were highly squamous intraepithelial lesions (HSIL,0.75 %).290 pregnant women received 8 weeks postpartum follow-up,which showed 87 cases of TCT≥ASC-US (30.00%) and a significant reduction from pregnancy (P<0.01).434 pregnant women took the HPV test,and 157 cases were HPV positive (36.18%).172 cases were followed up after birth,and 52 cases were HPV positive (30.23%).The difference was not statistically significant.Those with prenatal HPV infection and abnormal TCT,the rate of abnormal TCT postpartum was higher than that of those without prenatal HPV infection.The difference was statistically significant (P=0.001).Conclusions:Cervical cytology abnormality during gestation is often downgraded postpartum.Antepartum HPV infection can reduce the possibility of normal postoatrum TCT,which calls for clinical attention.

关键词

妊娠期/TCT/HPV/宫颈病变/分娩方式

Key words

gestation period/TCT/HPV/cervical cytology abnormality/delivery modes

分类

医药卫生

引用本文复制引用

许颖,李柱南,陈忆,欧阳婧,李冬,吴丹..妊娠期宫颈液基细胞学检查异常孕妇产后的临床转归[J].中国临床医学,2017,24(5):701-704,4.

基金项目

上海交通大学医工(理)交叉基金(YG2016QN46).Supported by Shanghai Jiao Tong University Medical Engineering Cross Fund (YG2016QN46). (理)

中国临床医学

OACSTPCD

1008-6358

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