中国临床医学2017，Vol.24Issue(5)：808-815,8.DOI:10.12025/j.issn.1008-6358.2017.20170223
人黑素瘤药物研究进展
Clinical treatment of human melanoma: recent progress
摘要
Abstract
The mortality rate of melanoma is high.Chemotherapy became the main treatment during the past years besides traditional surgical excision and radiotherapy.In recent years,with the in depth study of the molecular mechanism of the occurrence and development of melanoma,new treatment methods and medicines basing on the target therapy and immune therapy have emerged constantly.At present,in addition to the drugs that have been used in clinical treatment,some of the drugs that are being approved for clinical research and the potential drugs which are still in basic research show good application prospects.In this paper,the molecular mechanism and therapeutic effect of the representative drugs or potential drugs in the treatment of melanoma were reviewed.关键词
黑素瘤/多药联合治疗/生物免疫治疗/靶向治疗Key words
melanoma/multi-drug combination therapy/biological immunotherapy/targeted therapy分类
医药卫生引用本文复制引用
付靖波,于斌,张红霞,朱海英..人黑素瘤药物研究进展[J].中国临床医学,2017,24(5):808-815,8.基金项目
国家自然科学基金(31471284).Supported by National Natural Science Foundation of China(31471284). （31471284）
