中国实验动物学报2018，Vol.26Issue(1)：128-132,5.DOI:10.3969/j.issn.1005-4847.2018.01.020
糖尿病足神经病变动物模型研究进展
Advances in research of animal models of diabetic foot neuropathy
摘要
Abstract
Diabetic foot with diabetic peripheral neuropathy(DPN)can lead to peripheral nerve dysfunction. Ex-ploring appropriate animal models of the disease can make a better understanding of the occurrence, development, patho-genesis,prevention and treatment of DPN. Therefore,a reasonable construction of animal models is related to the success of experimental research. Up to date, experimental animals used in the research of diabetic foot neuropathy include rats, nude mice,transgenic mice,and so on. Nerve injury models can be generated by different means,such as ischemia reper-fusion,resection or ligation of nerves and scalds. This article will review the recent research progress of diabetic foot neu-ropathy animal models.关键词
糖尿病足/动物模型/神经病变/发病机制Key words
diabetic foot/animal model/peripheral neuropathy/pathogenesis分类
生物科学引用本文复制引用
李丹,陈龙菊..糖尿病足神经病变动物模型研究进展[J].中国实验动物学报,2018,26(1):128-132,5.基金项目
国家自然科学基金资助项目(No.81260192).Funded by National Natural Science Foundation of China(No.81260192). （No.81260192）
