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甲苯胺蓝在口腔医学中的应用及研究现状

闫素琴 庄德舒 毕良佳

中国实用口腔科杂志2017,Vol.10Issue(12):743-747,5.
中国实用口腔科杂志2017,Vol.10Issue(12):743-747,5.DOI:10.19538/j.kq.2017.12.009

甲苯胺蓝在口腔医学中的应用及研究现状

Application and research situation of toluidine blue in oral medicine

闫素琴 1庄德舒 1毕良佳1

作者信息

  • 1. 哈尔滨医科大学附属第四医院,黑龙江哈尔滨150000
  • 折叠

摘要

Abstract

Toluidine blue (TB),an alkaline thiazide cationic dye,which can be combined with the acidic substances in the tissue cells,is an important dye for nucleic acid staining.Because of the specific binding of TB to nucleic acids,TB can be retained in cancer tissue preferentially and widely used in the diagnosis of malignant tumors of the mouth,the eye,and the upper digestive tract.TB plays an important role in medical research.In addition,as an effective photosensitizer,TB can be widely used in photodynamic antimicrobial and antitumor therapy.The purpose of this review is to provide a summary about the research situation and the application of TB in oral medicine.

关键词

甲苯胺蓝/抗微生物/抗肿瘤/光动力疗法

Key words

toluidine blue, TB/antimicrobial/antitumor/photodynamic therapy

分类

医药卫生

引用本文复制引用

闫素琴,庄德舒,毕良佳..甲苯胺蓝在口腔医学中的应用及研究现状[J].中国实用口腔科杂志,2017,10(12):743-747,5.

基金项目

国家自然科学基金(81670994) (81670994)

中国实用口腔科杂志

OACSTPCD

1674-1595

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