中国现代医学杂志2018，Vol.28Issue(6)：109-113,5.DOI:10.3969/j.issn.1005-8982.2018.06.021
高频深部热疗在老年晚期卵巢癌合并腹腔积液患者中的应用
Efficacy of high frequency deep hyperthermia combined with GP regimen in treatment of advanced ovarian cancer complicated with peritoneal effusion
靳紫薇 1龚丽娜 2王松峰3
作者信息
- 1. 青海省红十字医院 妇科,青海 西宁 810000
- 2. 新疆维吾尔自治区人民医院 产科,新疆 乌鲁木齐 830001
- 3. 新疆医科大学第一附属医院 生殖医学科,新疆 乌鲁木齐 830054
- 折叠
摘要
Abstract
Objective To explore the effect of high frequency deep hyperthermia combined with GP regimen chemotherapy in the treatment of advanced ovarian cancer with peritoneal effusion. Methods A total of 60 cases of OCC treated with cytoreductive surgery were divided into control group (GP intraperitoneal chemotherapy) and observation group (high frequency deep hyperthermia plus GP intraperitoneal chemotherapy) randomly. The short-term efficacy, toxic and side effect, quality of life and the serum levels of HE4, CA125 and CEA were compared. Results The short-term efficacy was significantly higher in the observation group than that in the control group (P < 0.05). Both two groups had no serious toxic and side effect. Incidence of toxic and adverse reaction of the 2 groups had no significant difference. Life quality improvement rate of the observation group was significantly higher than that of the control group (P > 0.05). KPS score of the observation group was significantly higher than that of the control group (P < 0.05) after treatments. Serum levels of HE4, CA125 and CEA were significantly lower in the observation group than those in the control group after treatment (P < 0.05). Conclusion High frequency hyperthermia plus GP intraperitoneal chemotherapy was effective and safe for old OCC patients, which can improve the quality of life and decrease the serum levels of HE4, CA125 and CEA.关键词
高频深部热疗/GP方案/卵巢癌/腹腔积液Key words
high frequency hyperthermia/GP intraperitoneal chemotherapy/oophoroma/peritoneal effusion分类
医药卫生引用本文复制引用
靳紫薇,龚丽娜,王松峰..高频深部热疗在老年晚期卵巢癌合并腹腔积液患者中的应用[J].中国现代医学杂志,2018,28(6):109-113,5.
