中国畜牧兽医2017，Vol.44Issue(11)：3300-3305,6.DOI:10.16431/j.cnki.1671-7236.2017.11.027
菌落突变株与细菌适应性生存关系研究进展
Research Progress on Adaptive Survival Relationship Between Small Colony Variants and Bacteria
摘要
Abstract
Small colony variants (SCVs) have been shown to be part of the regular growth cycle,which are highly dynamic or stable and can be selected during various harsh conditions.The features of SCVs include slow growth,colony morphology irregular and biochemical characteristics abnormal,making the separation and identification of SCVs into trouble.SCVs can cause chronic persistent infection,but not lead to strong immune response to host.Furthermore,SCVs are serious resistant to antibacterials normally.In this paper,we introduce the phenotype classification of SCVs,the relationship with the host's immune response and the effects of antibacterials on SCVs,which will provide theoretical support for further research of SCVs.关键词
小菌落突变株/表型/免疫反应/耐药性Key words
small colony variants/phenotype/immune response/antibiotics resistance分类
医药卫生引用本文复制引用
高翔,郭玉茹,杨杰,黄程程,田春莲,宏伟,刘明春..菌落突变株与细菌适应性生存关系研究进展[J].中国畜牧兽医,2017,44(11):3300-3305,6.基金项目
国家自然科学基金(31572564) （31572564）
