中国药理学通报2018，Vol.34Issue(2)：149-153,5.DOI:10.3969/j.issn.1001-1978.2018.02.001
肿瘤微环境中髓样细胞对肿瘤的作用及机制研究进展
Research progress in role of myeloid cells in tumor microenvironment and its mechanisms
摘要
Abstract
In recent years,a large number of studies have shown that myeloid cells in tumor microenvironment play an important role in tumorigenesis and tumor progression.On one hand,myeloid cells can regulate human immune system;on the other hand,myeloid cells can influence tumor progression,metastasis and clinical treatments.In this review,we summarize the interaction between myeloid cells and tumors,discuss the effects of myeloid cells after recruited to tumor sites and its mechanisms,try to put forward clinical therapy targeting myeloid cells and provide references for the following research and clinical treatments.关键词
肿瘤/肿瘤微环境/髓样细胞/免疫系统/作用机制/靶向疗法Key words
tumor/tumor microenvironment/myeloid cells/immune system/mechanisms/targeted therapy分类
医药卫生引用本文复制引用
吴佳伟,曹玉珠,余苏云,张婷婷,杨宇,陈文星,王爱云,陆茵..肿瘤微环境中髓样细胞对肿瘤的作用及机制研究进展[J].中国药理学通报,2018,34(2):149-153,5.基金项目
国家自然科学基金资助项目(No 81403260,81573859,81673725,81673648) （No 81403260,81573859,81673725,81673648）
中国博士后科学基金资助项目(No 2014M551639) （No 2014M551639）
江苏省博士后基金资助项目(No 1401138C) （No 1401138C）
江苏高校优秀科技创新团队计划[苏教科(2013)10号文] （2013）
江苏高校品牌专业建设工程资助项目(No PPZY2015A070) （No PPZY2015A070）
江苏高校中药学优势学科建设工程资助项目(PAPD)[苏政办发(2014)37号文] （PAPD）
