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脑源性神经营养因子与抑郁症

关书 熊伟 高云

中国药理学通报2018,Vol.34Issue(2):153-156,4.
中国药理学通报2018,Vol.34Issue(2):153-156,4.DOI:10.3969/j.issn.1001-1978.2018.02.002

脑源性神经营养因子与抑郁症

Brain-derived neurotrophic factor and depression

关书 1熊伟 2高云1

作者信息

  • 1. 南昌大学基础医学院生理学教研室,江西南昌330006
  • 2. 南昌大学附属口腔医院预防科,江西南昌330019
  • 折叠

摘要

Abstract

Brain-derived neurotrophic factor (BDNF) is an important member of the neurotrophic factor family,which can promote and maintain the process of development and regeneration of nervous system.Recent studies have shown that BDNF plays an important role in the diagnosis and treatment of depression and the complications.In this paper,the role of BDNF,its receptors and signal transduction pathways in depression,the comorbidity of diabetes and depression,the comorbidity of stroke and depression,postpartum depression,and the comorbidity of chronic pain and depression are discussed.

关键词

脑源性神经营养因子/抑郁症/糖尿病/脑卒中/产后抑郁症/慢性疼痛

Key words

brain-derived neurotrophic factor/depression/diabetes/stroke/postpartum depression/chronic pain

分类

医药卫生

引用本文复制引用

关书,熊伟,高云..脑源性神经营养因子与抑郁症[J].中国药理学通报,2018,34(2):153-156,4.

基金项目

国家自然科学基金资助项目(No 81100829,81360136,81460106,81760152) (No 81100829,81360136,81460106,81760152)

江西省主要学科学术和技术带头人培养计划项目(No 20142BCB22001) (No 20142BCB22001)

中国药理学通报

OA北大核心CSCDCSTPCD

1001-1978

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