中国药理学通报2018，Vol.34Issue(2)：170-173,4.DOI:10.3969/j.issn.1001-1978.2018.02.006
SIRT6在心血管疾病中的作用研究进展
Research progress of SIRT6 in cardiovascular diseases
摘要
Abstract
Cardiovascular disease is a serious disease harmful to human health with high morbidity and high mortality.SIRT6 plays an important role in cardiovascular diseases such as atherosclerosis,myocardial infarction and ischemia/reperfusion injury,pathological cardiac hypertrophy and heart failure,as an important member of the histone deacetylase family.In this paper,the role of SIRT6 in cardiovascular diseases is reviewed,and the development of SIRT6 as a target agonist and inhibitor is summarized.关键词
SIRT6/去乙酰化/动脉粥样硬化/心肌梗死/心肌肥大/激动剂/抑制剂Key words
SIRT6/deacetylation/atherosclerosis/myocardial infarction/cardiac hypertrophy/agonist/inhibitor分类
医药卫生引用本文复制引用
张晓英,张致英..SIRT6在心血管疾病中的作用研究进展[J].中国药理学通报,2018,34(2):170-173,4.基金项目
西藏自治区科技厅自然基金资助项目(No 2016ZR-MQ-06) （No 2016ZR-MQ-06）
