中国医学装备2018，Vol.15Issue(2)：47-50,4.DOI:10.3969/J.ISSN.1672-8270.2018.02.013
脑胶质瘤共面、非共面容积旋转调强及螺旋断层放射治疗技术的剂量学比较研究
A comparative study on the dosimetry of coplanar VMAT, non-coplanar VMAT and tomotherapy for brain glioma
摘要
Abstract
Objective: To compare the differences of dosimetry among coplanar volumetric modulated arc therapy (VMAT), non-coplanar VMAT and tomotherapy for patients with brain glioma at post operation, and evaluate the differences of different radiotherapy plan. Methods: The CT images of 7 patients with brain glioma were collected, and the target area, the endangered organs and normal tissue were sketched on the cross section of magnetic resonance imaging (MRI) by attending doctor. Three radiotherapy plans included of coplanar VMAT, non-coplanar VMAT and tomography (TOMO) were formulated for each case, and all of cases were divided into coplanar VMAT group, non-coplanar VMAT group and TOMO group. The prescription of radiotherapy was 60Gy/30F and the edema area was 54Gy/30F. The evaluation index included:①maximum dose (Dmax)of PGTV and Dmaxof PCTV, average dose (Dmean) and minimum dose (Dmin). ②homogeneity index (HI) and conformity index (CI). 3)The Dmaxand Dmeanthat endangered organ. The differences of three evaluation indexes among the three groups were compared. Results: When the target area was under the different planning model, the three groups planning could well meet the requirements of target area. The HI of TOMO planning group was slightly better than that of other two groups. And the CI of the three groups was no significant difference. For brain glioma, the mean values of PCTV Dmeanand PGTV Dmeanof TOMO plan were significantly lower than that of coplanar VMAT group and non-coplanar VMAT group, respectively (F=6.500, F=12.755, P<0.05), and it was more closer to the requirement of prescription. Conclusion: For different parts of the glioma, all of the coplanar VMAT, non-coplanar VMAT and TOMO under radiotherapy planning system of Varian Eclipse can meet the requirement of dose coverage, homogeneity and conformity in target area. And TOMO has better protective effect for endangered organ than other two plans.关键词
心脏除颤器/释放能量/数据分析/失准/除颤分析仪Key words
Brain glioma/Non-coplanar volumetric arc intensity modulated therapy/Volumetric arc intensity modulated therapy/Tomotherapy/Dosimetry分类
医药卫生引用本文复制引用
王宇,吴文,许敬辉,廖雄飞,黎杰,陈亚正..脑胶质瘤共面、非共面容积旋转调强及螺旋断层放射治疗技术的剂量学比较研究[J].中国医学装备,2018,15(2):47-50,4.基金项目
四川省青年基金(2015JQ0053)"现代放疗技术引发第二原发癌风险的辐射剂量因素研究" （2015JQ0053）
四川省卫生和计划生育委员会课题(16PJ517)"医用加速器高档位能量(>10 MV)产生的中子辐射测试研究" （16PJ517）
四川省干部保健科研课题(川干研2017-802)"术中放疗加速器在手术过程中的中子剂量跟踪研究" （川干研2017-802）
