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自噬在结直肠癌发生及防治中作用的研究进展

孙悦 曹海龙 姜葵 王邦茂

肿瘤药学2018,Vol.8Issue(1):1-6,30,7.
肿瘤药学2018,Vol.8Issue(1):1-6,30,7.DOI:10.3969/j.issn.2095-1264.2018.01.01

自噬在结直肠癌发生及防治中作用的研究进展

Research Progress of Autophagy in the Development and Treatment for Colorectal Cancer Patients

孙悦 1曹海龙 1姜葵 1王邦茂1

作者信息

  • 1. 天津医科大学总医院 消化内科,天津,300052
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摘要

Abstract

Autophagy is a highly conserved lysosomal degradation pathway which contributes to maintain the intracellular homeostasis. This process is closely related to various diseases including cancer. More evidences have showed that autophagy plays a complex role in the development and therapy of colorectal cancer (CRC), and closely related to the prognosis of CRC. The present article summarized the recent advances in the double-edged role and anti-cancer potential of autophagy for the colorectal cancer patients.

关键词

自噬/结直肠癌/肿瘤发生/治疗/预后

Key words

Autophagy/Colorectal cancer/Carcinogenesis/Therapy/Prognosis

分类

医药卫生

引用本文复制引用

孙悦,曹海龙,姜葵,王邦茂..自噬在结直肠癌发生及防治中作用的研究进展[J].肿瘤药学,2018,8(1):1-6,30,7.

基金项目

国家自然科学基金(81470796,81570478). (81470796,81570478)

肿瘤药学

OACSTPCD

2095-1264

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